The body's immunity is an integral system when it comes to fighting infections. At times, the cells in the system are too active and target the body's connective tissues which result in inflammation that is long-term. Eczema patient's skin barrier is impaired so they tend to have dry skin which makes a way for the natural oils that moisturize the skin to leak and environmental allergens can into the flesh. This when the immune-fighting cells that are in the skin are triggered into hyperactivity and the swelling and redness are accompanied by the itchiness. These are the common symptoms of eczema. Methotrexate for eczema is used because it has the ability to slow down the over-activity of the immune system's cells thus reducing the inflammation and the itching. Methotrexate can be administered as a standalone treatment or it can be combined with other treatments.
As a disclaimer, while we do our best to make sure all info is accurate, check with your healthcare provider before attempting any new treatment.
How to Take Methotrexate for Eczema?
Taking this medication under the direct supervision of a doctor with a specialization. Your dermatologist should directly monitor you while on Methotrexate unless you are taking it for more than one reason, such as for rheumatoid arthritis as well, in which case your rheumatologist can monitor the effects of the medication.
Methotrexate Side Effects
Most patients who take Methotrexate don't have the serious side effects that cause them to have to discontinue treatment using the medication. If side effects do occur, most of the time and they are minor and they go away as the treatment progresses. The side effect that is most commonly experienced is nausea. This normally starts on the first day of treatment. Turn to your physician if you experience nausea symptoms. Over-the-counter folic acid can help ease these symptoms. Your doctor can also prescribe medication that will counteract nausea symptoms or change your dosage from oral medication to injections.
There is a possibility of liver function abnormalities occurring as well as CBC numbers that are out of range. This occurs mostly during the first couple of weeks of treatment. Your specialist should give you blood tests on a regular basis to be sure that you aren't having any problems. The blood tests will be more often during the initial onset of treatment and will become fewer the longer you have been taking Methotrexate. These problems normally happen when the patient is taking higher dosages of Methotrexate but it can happen on lower doses as well.
This medication is immunosuppressant so the patients taking it can be prone to getting infections easily. Eczema patients are susceptible to skin infections that are viral like cold sores. A flu shot is also recommended for patients taking Methotrexate. If you have a fever or a sore throat and get any other infections (including skin infections). You should also make your doctor aware if you are experiencing bleeding or bruising that cannot be accounted for. Most of the time the infections ease up after the patient has been taking the medication for a while and the eczema flares are fewer and farther between.
It is possible for Methotrexate for Eczema to cause liver scarring although the side effect is rare. The likelihood of this occurring is higher in patients that are overweight and diabetic or they have pre-existing liver conditions. If a patient is already on medication that can cause toxic effects on the liver, Methotrexate can cause fibrosis as well.